This study sought to identify acoustic variables explaining rate-related variation in intelligibility for speakers with dysarthria for sentences produced at habitual and a slower than normal rate. Four speakers with dysarthria due to Multiple Sclerosis (MS) produced the same 25 Harvard sentences at habitual and slow rates. Speakers were selected from a larger corpus based on intelligibility characteristics. Two speakers demonstrated improved intelligibility and two speakers demonstrated reduced intelligibility when rate was slowed. A speech-analysis resynthesis paradigm termed hybridization was used in which segmental (i.e. short-term spectral) and suprasegmental variables (i.e. sentence-level fundamental frequency, energy characteristics, duration) were manipulated individually or in combination. Six hybridized sentence types were studied. On-line crowd-sourced orthographic transcription was used to quantify intelligibility for hybridized stimuli and the original habitual and slow productions. The results indicated that combined changes in short-term spectrum and duration affect intelligibility variation associated with a slowed rate.